Recombinant Human BAFF

貨號:

310-13

品牌:

Peprotech

規格:

20μg

概述

人BAFF細胞因子 B cell Activating Factor belonging to the TNF family, TNFSF13B, TNFSF20, TALL-1, BLyS, THANK, ZNTF4

研究領(lǐng)域:

細胞生物學(xué)

詳述

,配體TNF家族的一員,表示在T細胞,巨噬細胞、單核細胞和樹(shù)突細胞。高飛球的一擊是參與刺激B細胞和T細胞的功能,是一個(gè)重要的生存和外圍B細胞的成熟因素。高飛球的一擊信號通過(guò)三個(gè)不同的TNF受體、TACI BCMA BAFF-R。人類(lèi)的高飛球的一擊基因編碼一個(gè)285個(gè)氨基酸II型包含46個(gè)氨基酸胞質(zhì)域的跨膜蛋白,21個(gè)氨基酸跨膜域和218氨基酸細胞外的領(lǐng)域。重組人可溶性高飛球的一擊是152氨基酸多肽(17.0 kDa),其中包含的TNF-like部分細胞外領(lǐng)域?

BAFF, a member of the TNF family of ligands, is expressed in T cells, macrophages, monocytes and dendritic cells. BAFF is involved in stimulation of B and T cell function, and is an important survival and maturation factor for peripheral B cells. BAFF signals through three different TNF receptors, TACI, BCMA and BAFF-R. The human BAFF gene codes for a 285 amino acid type II transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain. Recombinant Human soluble BAFF is a 152 amino acid polypeptide (17.0 kDa), which contains the TNF-like portion of the extracellular domain of BAFF.

氨基酸序列:

AVQGPEETVT QDCLQLIADS ETPTIQKGSY TFVPWLLSFK RGSALEEKEN KILVKETGYF FIYGQVLYTD KTYAMGHLIQ RKKVHVFGDE LSLVTLFRCI QNMPETLPNN SCYSAGIAKL EEGDELQLAI PRENAQISLD GDVTFFGALK LL

來(lái)源:

E.coli

純度:

Greater than 95% by SDS-PAGE gel and HPLC analyses.

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Wolcavi Biotech致力于干細胞免疫治療、分子生物學(xué) 、免疫學(xué)、體外診斷等相關(guān)領(lǐng)域的實(shí)驗需求產(chǎn)品開(kāi)發(fā)和銷(xiāo)售。主要產(chǎn)品有抗原抗體|無(wú)血清培養基|細胞培養耗材并代理銷(xiāo)售Abcam、Invitrogen(Gibco)、Roche、Sigma、R&D、Meridian等二十多家國外知名品牌。

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Recombinant Human BAFF